Assessing Cardiovascular Risk by Using the Fat Attenuation Index in Coronary CT Angiography

Coronary CT angiography (CCTA) has evolved into a first-line diagnostic test for the investigation of chest pain. Despite advances toward standardising the reporting of CCTA through the Coronary Artery Disease Reporting and Data System (or CAD-RADS) tool, the prognostic value of CCTA in the earliest stages of atherosclerosis remains limited.
Perivascular adipose tissue mapping by means of the coronary CT angiography (CCTA)–derived fat attenuation index is a recently developed method to non-invasively detect coronary inflammation and atherosclerotic changes at CCTA, with incremental prognostic value over and above traditional risk factors.
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Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers: A clinical consensus statement from the European Society of Cardiology Working Group on Coronary Pathophysiology and Micro-circulation
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