Cardiovascular computed tomography imaging for coronary artery disease risk: plaque, flow and fat
CCTA has emerged as the preferred non-invasive modality for the study of chest pain due to possible underlying CAD, and for the assessment of cardiovascular risk. Technical advances and realignment of patient pathways make CCTA a first-line investigation for assessment of CAD.Perivascular fat attenuation is a novel biomarker of coronary artery inflammation that can be evaluated from routine CCTA. It has the potential to predict coronary risk, above and beyond plaque features or stenosis, and is able to reclassify a substantial proportion of patients.
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October 2023
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers: A clinical consensus statement from the European Society of Cardiology Working Group on Coronary Pathophysiology and Micro-circulation
This clinical consensus statement from the European Society of Cardiology defines perivascular adipose tissue (PVAT) and highlights the biological mechanisms…
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October 2023
SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels
Abstract: Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic cardiovascular complications up to 1 year after infection. Although…