Detecting Coronary Inflammation with Perivascular Fat Attenuation Imaging: Making Sense from Perivascular Attenuation Maps

Inflammation has long been implicated in human atherogenesis, which has been confirmed by recent clinical trials. Although simple therapeutic interventions such as statins reduce vascular inflammation, significant residual inflammatory risk remains.
Noninvasive imaging using positron emission tomography (PET) can indirectly detect coronary inflammation, but is expensive and requires high-end equipment. The development of more accessible noninvasive imaging methods to identify coronary inflammation would allow targeted deployment of anti-inflammatory treatments, which would facilitate a more personalized approach to individual care.
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March 2023
Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy
In these contemporary data from 31 245 patients who are receiving statin therapy, residual inflammatory risk appears to be more…
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March 2023
Pericoronary Adipose Tissue as a Marker of Cardiovascular Risk
JACC Review Topic of the Week. In this review the authors aim to summarize the role of PCAT in cardiac…