Perivascular Fat Attenuation Index by Computed Tomography as a Metric of Coronary Inflammation
We read with interest the study of Ohyama et al. that linked vasospastic angina with perivascular adipose tissue (PVAT) volume and inflammation. The role of PVAT in vascular disease pathogenesis is currently well-accepted and supported by both translational and clinical evidence. Nonetheless, the findings of Ohyama et al. are important because they highlight the role of PVAT in aspects of coronary pathophysiology beyond atherosclerosis. Evidence of coronary PVAT inflammation by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18FFDG PET/CT) imaging could be used in the diagnosis of vasospastic angina.
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March 2023
Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy
In these contemporary data from 31 245 patients who are receiving statin therapy, residual inflammatory risk appears to be more…
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March 2023
Pericoronary Adipose Tissue as a Marker of Cardiovascular Risk
JACC Review Topic of the Week. In this review the authors aim to summarize the role of PCAT in cardiac…