Peri-Coronary Adipose Tissue Density Is Associated With 18F-Sodium Fluoride Coronary Uptake in Stable Patients With High-Risk Plaques

The validity of our novel biomarker, the Fat Attenuation Index (FAI), has recently been confirmed in a study by Kwiecinski et al, published in the Journal of the American College of Cardiology: Cardiovascular Imaging. This international study showed that changes in perivascular adipose tissue density assessed using CCTA were strongly correlated with coronary inflammation assessed using 18F-sodium fluoride PET imaging.

This is exciting confirmation of our methodology, and two of Caristo’s founders, Professor Charalambos Antoniades and Dr. Cheerag Shirodaria have written an editorial to accompany this important publication. We are pleased to see independent validation of our work from a leading global CCTA research group. FAI remains poised to become a game-changing refinement of cardiovascular risk prediction, and we look forward to future studies further establishing FAI as an essential tool for the future of cardiovascular disease management.

Read Kwiecinski et al.

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