Constructing Custom-made Radiotranscriptomic Signatures of Vascular Inflammation from Routine CT Angiograms: A Prospective Outcomes study in COVID-19
Direct evaluation of vascular inflammation in patients with COVID-19 would facilitate more efficient trials of new treatments and identify patients at risk of long-term complications who might respond to treatment. We aimed to develop a novel artificial intelligence (AI)-assisted image analysis platform that quantifies cytokine-driven vascular inflammation from routine CT angiograms, and sought to validate its prognostic value in COVID-19.
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October 2023
Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers: A clinical consensus statement from the European Society of Cardiology Working Group on Coronary Pathophysiology and Micro-circulation
This clinical consensus statement from the European Society of Cardiology defines perivascular adipose tissue (PVAT) and highlights the biological mechanisms…
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October 2023
SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels
Abstract: Patients with coronavirus disease 2019 (COVID-19) present increased risk for ischemic cardiovascular complications up to 1 year after infection. Although…